Bus Karlovy Vary to Brno: Compare prices and save money

Compare all timetables for the bus from Karlovy Vary to Brno

Here is a selection of the cheapest bus trips from the schedule from Karlovy Vary to Brno from various bus operators like RegioJet or FlixBus for the next days.

today

$19

tomorrow

$15

Thursday

$15

Friday

$16

Saturday

$19

Sunday

$16

Monday

$19

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
RegioJet	12h 40m	8:00 PM	Karlovy Vary	Bus Station	8:40 AM	Brno	Train station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/21/2026 8:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/22/2026 8:40:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 12h 40m
RegioJet	5h 30m	8:00 PM	Karlovy Vary	Bus Station	1:30 AM	Brno	Benesova Bus Station	Economy	$24	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/21/2026 8:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 7/22/2026 1:30:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 5h 30m
RegioJet	11h 15m	8:00 PM	Karlovy Vary	Bus Station	7:15 AM	Brno	Královo Pole Train Station	Economy	$25	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/21/2026 8:00:00 PM to Královo Pole Train Station, Brno (Czech Republic) arriving at 7/22/2026 7:15:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 11h 15m
RegioJet	13h 0m	6:00 PM	Karlovy Vary	Bus Station	7:00 AM	Brno	Train station	Economy	$47	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/21/2026 6:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/22/2026 7:00:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 13h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	5:55 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$15	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/22/2026 5:55:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/22/2026 12:10:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 15m
FlixBus	5h 55m	6:15 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$15	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/22/2026 6:15:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/22/2026 12:10:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 55m
FlixBus	5h 10m	9:30 AM	Karlovy Vary	Bus Station	2:40 PM	Brno	Hotel Grand	Economy	$15	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/22/2026 9:30:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/22/2026 2:40:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 5h 10m
RegioJet	13h 30m	8:00 PM	Karlovy Vary	Bus Station	9:30 AM	Brno	Benesova Bus Station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/22/2026 8:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 7/23/2026 9:30:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 13h 30m
RegioJet	12h 40m	8:00 PM	Karlovy Vary	Bus Station	8:40 AM	Brno	Train station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/22/2026 8:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/23/2026 8:40:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 12h 40m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	5:55 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$15	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/23/2026 5:55:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/23/2026 12:10:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 6h 15m
FlixBus	4h 50m	4:10 PM	Karlovy Vary	Bus Station	9:00 PM	Brno	Hotel Grand	Economy	$15	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/23/2026 4:10:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 7/23/2026 9:00:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 4h 50m
FlixBus	5h 55m	6:15 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$18	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/23/2026 6:15:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/23/2026 12:10:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 5h 55m
RegioJet	12h 40m	8:00 PM	Karlovy Vary	Bus Station	8:40 AM	Brno	Train station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/23/2026 8:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/24/2026 8:40:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 12h 40m
RegioJet	5h 37m	3:00 PM	Karlovy Vary	Bus Station	8:37 PM	Brno	Židenice	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/23/2026 3:00:00 PM to Židenice, Brno (Czech Republic) arriving at 7/23/2026 8:37:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 37m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	5:55 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$16	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/24/2026 5:55:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/24/2026 12:10:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 15m
FlixBus	4h 50m	4:10 PM	Karlovy Vary	Bus Station	9:00 PM	Brno	Hotel Grand	Economy	$16	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/24/2026 4:10:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 7/24/2026 9:00:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 4h 50m
RegioJet	12h 40m	8:00 PM	Karlovy Vary	Bus Station	8:40 AM	Brno	Train station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/24/2026 8:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/25/2026 8:40:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 12h 40m
FlixBus	5h 55m	6:15 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$20	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/24/2026 6:15:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/24/2026 12:10:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 55m
RegioJet	6h 12m	5:00 PM	Karlovy Vary	Bus Station	11:12 PM	Brno	Židenice	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/24/2026 5:00:00 PM to Židenice, Brno (Czech Republic) arriving at 7/24/2026 11:12:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 6h 12m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
RegioJet	12h 40m	8:00 PM	Karlovy Vary	Bus Station	8:40 AM	Brno	Train station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/25/2026 8:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/26/2026 8:40:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 12h 40m
RegioJet	13h 14m	8:00 PM	Karlovy Vary	Bus Station	9:14 AM	Brno	Královo Pole Train Station	Economy	$20	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/25/2026 8:00:00 PM to Královo Pole Train Station, Brno (Czech Republic) arriving at 7/26/2026 9:14:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 13h 14m
RegioJet	5h 40m	2:00 PM	Karlovy Vary	Bus Station	7:40 PM	Brno	Train station	Economy	$20	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/25/2026 2:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/25/2026 7:40:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 5h 40m
RegioJet	6h 14m	2:00 PM	Karlovy Vary	Bus Station	8:14 PM	Brno	Královo Pole Train Station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/25/2026 2:00:00 PM to Královo Pole Train Station, Brno (Czech Republic) arriving at 7/25/2026 8:14:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 6h 14m
RegioJet	5h 42m	3:00 PM	Karlovy Vary	Bus Station	8:42 PM	Brno	Train station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/25/2026 3:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/25/2026 8:42:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 42m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 15m	5:55 AM	Karlovy Vary	Bus Station	12:10 PM	Brno	Hotel Grand	Economy	$16	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/26/2026 5:55:00 AM to Hotel Grand, Brno (Czech Republic) arriving at 7/26/2026 12:10:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 6h 15m
FlixBus	4h 50m	4:10 PM	Karlovy Vary	Bus Station	9:00 PM	Brno	Hotel Grand	Economy	$16	A Bus from FlixBus goes from Bus Station, Karlovy Vary (Czech Republic) at 7/26/2026 4:10:00 PM to Hotel Grand, Brno (Czech Republic) arriving at 7/26/2026 9:00:00 PM. 50 Economy ticket for $16 per person are available. Travel duration is 4h 50m
RegioJet	6h 12m	5:00 PM	Karlovy Vary	Bus Station	11:12 PM	Brno	Židenice	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/26/2026 5:00:00 PM to Židenice, Brno (Czech Republic) arriving at 7/26/2026 11:12:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 6h 12m
RegioJet	6h 17m	5:00 PM	Karlovy Vary	Bus Station	11:17 PM	Brno	Train station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/26/2026 5:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/26/2026 11:17:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 6h 17m
RegioJet	12h 40m	8:00 PM	Karlovy Vary	Bus Station	8:40 AM	Brno	Train station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/26/2026 8:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/27/2026 8:40:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 12h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
RegioJet	5h 42m	3:00 PM	Karlovy Vary	Bus Station	8:42 PM	Brno	Train station	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/27/2026 3:00:00 PM to Train station, Brno (Czech Republic) arriving at 7/27/2026 8:42:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 42m
RegioJet	5h 37m	3:00 PM	Karlovy Vary	Bus Station	8:37 PM	Brno	Židenice	Economy	$19	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/27/2026 3:00:00 PM to Židenice, Brno (Czech Republic) arriving at 7/27/2026 8:37:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 37m
RegioJet	5h 55m	1:00 PM	Karlovy Vary	Bus Station	6:55 PM	Brno	Benesova Bus Station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/27/2026 1:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 7/27/2026 6:55:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 55m
RegioJet	5h 30m	3:00 PM	Karlovy Vary	Bus Station	8:30 PM	Brno	Benesova Bus Station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/27/2026 3:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 7/27/2026 8:30:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 30m
RegioJet	5h 55m	4:00 PM	Karlovy Vary	Bus Station	9:55 PM	Brno	Benesova Bus Station	Economy	$21	A Bus from RegioJet goes from Bus Station, Karlovy Vary (Czech Republic) at 7/27/2026 4:00:00 PM to Benesova Bus Station, Brno (Czech Republic) arriving at 7/27/2026 9:55:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 5h 55m

Frequency of bus connections between Karlovy Vary and Brno

See here how frequent the connections between Karlovy Vary and Brno are, during different times and days of the week.

Wednesday is the busiest day, with more than 50 daily buses from Karlovy Vary to Brno. Tuesday has instead the fewest connections, with only 4 daily coaches between Karlovy Vary and Brno.

The busiest time of the day is the Morning, with 111 buses from Karlovy Vary to Brno, while Night sees the fewest connections between Karlovy Vary and Brno, with 12 offers.

Test cheapest views

The cheapest bus for the 8/5/2026 costs just $15, from FlixBus

Facts about the bus from Karlovy Vary to Brno

Compare all providers like RegioJet and FlixBus that travel 35 times every day by bus from Karlovy Vary to Brno in one click! Book your bus ticket from Karlovy Vary to Brno starting from $15!

Cheapest Bus	$15
Fastest Bus	4h 50m
Earliest Bus	6:00 PM
Latest Bus	8:00 PM
Daily Bus Routes	35 Ø
Distance	181.6 miles
Bus Companies	RegioJet and FlixBus

Cheapest bus connections from Karlovy Vary to Brno

Every day, 35 buses from 2 bus companies leave Karlovy Vary for Brno: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

$19

Wednesday 07/22

$19

Thursday 07/23

$15

Friday 07/24

$16

Saturday 07/25

$20

Sunday 07/26

$16

Monday 07/27

$22

Tuesday 07/28

$20

Wednesday 07/29

$21

Thursday 07/30

$24

Friday 07/31

$21

Saturday 08/01

$21

Sunday 08/02

$21

Monday 08/03

$15

Tuesday 08/04

Wednesday 08/05

$15

Thursday 08/06

$21

Friday 08/07

$16

Saturday 08/08

$20

Sunday 08/09

$22

Monday 08/10

$16

Tuesday 08/11

$19

Wednesday 08/12

$21

Thursday 08/13

Friday 08/14

$16

Saturday 08/15

The cheapest time to travel from Karlovy Vary to Brno

See here on which day and which time of the day you can find the cheapest bus ticket from Karlovy Vary to Brno, for the next 30 days.

With a price starting from $15, Wednesday is the cheapest day for a bus from Karlovy Vary to Brno. Tuesday instead is the most expensive day with prices starting from $19.

Morning is the cheapest day time for bus tickets from Karlovy Vary to Brno, with $15. Evening is the most expensive time of the day with prices starting from $19.

How to save money travelling from Karlovy Vary to Brno

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Karlovy Vary to Brno in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Karlovy Vary to Brno, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Karlovy Vary to Brno are also emptier.

All bus stations and stops in Karlovy Vary and Brno

In the map below, you can see where to find all bus stations in Karlovy Vary and Brno.

Bus Station

Západní 2080/2A

KV Arena Bus Stop

Penzion Šárka

Penzion U Karla IV.

Cihelny Golf & Wellness Resort Karlovy Vary by Axxos Hotels

Hotel Grand

Benešova

ÚAN Zvonařka

Zvonařka 470/2b

Stará Nemocnice

Kamenice

Ikea

Dolní Nádraží

Service and Comfort on the bus from Karlovy Vary to Brno

Want to know which seat classes are available on the buses from Karlovy Vary to Brno? Or which bus companies serve the route Karlovy Vary to Brno? Below you will find answers to your questions.

FAQs about the Karlovy Vary to Brno bus

How much does a Karlovy Vary Brno bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $15 and takes 5h 55m to reach Brno. Compare offers to save money!

How much could I save by comparing buses from Karlovy Vary to Brno?

This route is offered by 2 companies with a range of ticket prices between $15 and $49. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brno.

On average, how many connections are available from Karlovy Vary to Brno each day?

Every day, the Karlovy Vary to Brno bus route is served by approximately 35 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Karlovy Vary to Brno take?

The fastest bus from Karlovy Vary to Brno is offered by FlixBus and takes 4h 50m. Bus tickets for this connection cost $15. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Karlovy Vary to Brno?

The earliest bus arriving in Brno from Karlovy Vary starts at 6:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Karlovy Vary to Brno?

The latest bus trip departing from Karlovy Vary for Brno starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Karlovy Vary Brno route?

When traveling by bus from Karlovy Vary to Brno, passengers can travel with RegioJet and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Karlovy Vary and Brno?

You can check all the direct connections between Karlovy Vary and Brno by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: RegioJet and FlixBus.

What can I take with me on the Karlovy Vary to Brno bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Karlovy Vary Brno bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Karlovy Vary Brno bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Karlovy Vary to Brno on your planned travel date.

Available seat classes which are offered on the bus route Karlovy Vary to Brno

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Karlovy Vary and to Brno

Here’s an overview of the most popular bus routes to Karlovy Vary and to Brno. Simply click on the connection of your choice, and you will find all the details about your bus route!