Bus Gainesville, FL to Chicago: Compare prices and save money

Compare all timetables for the bus from Gainesville, FL to Chicago

Here is a selection of the cheapest bus trips from the schedule from Gainesville, FL to Chicago from various bus operators like FlixBus or Greyhound US for the next days.

today

$99

tomorrow

$106

Monday

$102

Tuesday

$105

Wednesday

Thursday

$116

Friday

$103

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 45m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	11:55 PM	Chicago	95th Red Line Station	Economy	$99	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/25/2026 1:10:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/25/2026 11:55:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 23h 45m
FlixBus	26h 10m	5:15 PM	Gainesville, FL	Rosa Parks Transfer station	6:25 PM	Chicago	95th Red Line Station	Economy	$100	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/25/2026 5:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/26/2026 6:25:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 26h 10m
FlixBus	24h 35m	11:30 AM	Gainesville, FL	Rosa Parks Transfer station	11:05 AM	Chicago	95th Red Line Station	Economy	$102	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/25/2026 11:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/26/2026 11:05:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 24h 35m
Greyhound US	27h 45m	8:20 AM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$103	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/25/2026 8:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/26/2026 11:05:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 27h 45m
Greyhound US	35h 5m	1:30 PM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:35 PM	Chicago	95th Red Line Station	Economy	$105	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/25/2026 1:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/26/2026 11:35:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 35h 5m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 35m	11:30 AM	Gainesville, FL	Rosa Parks Transfer station	11:05 AM	Chicago	95th Red Line Station	Economy	$106	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/26/2026 11:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 11:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 35m
FlixBus	23h 45m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	11:55 PM	Chicago	95th Red Line Station	Economy	$107	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/26/2026 1:10:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/26/2026 11:55:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 23h 45m
FlixBus	37h 30m	9:20 PM	Gainesville, FL	Rosa Parks Transfer station	9:50 AM	Chicago	95th Red Line Station	Economy	$107	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/26/2026 9:20:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 9:50:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 37h 30m
Greyhound US	27h 45m	8:20 AM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/26/2026 8:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 11:05:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 27h 45m
Greyhound US	35h 5m	1:30 PM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:35 PM	Chicago	95th Red Line Station	Economy	$116	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/26/2026 1:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 11:35:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 35h 5m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 45m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	11:55 PM	Chicago	95th Red Line Station	Economy	$102	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/27/2026 1:10:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/27/2026 11:55:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 45m
FlixBus	24h 0m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	12:10 AM	Chicago	Downtown Bus Station	Economy	$111	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/27/2026 1:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/28/2026 12:10:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 24h 0m
FlixBus	30h 30m	6:05 PM	Gainesville, FL	Rosa Parks Transfer station	11:35 PM	Chicago	95th Red Line Station	Economy	$112	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/27/2026 6:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 11:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 30h 30m
Greyhound US	35h 5m	1:30 PM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:35 PM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/27/2026 1:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 11:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 35h 5m
Greyhound US	27h 45m	8:20 AM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$113	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/27/2026 8:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 11:05:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 27h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 45m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	11:55 PM	Chicago	95th Red Line Station	Economy	$105	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/28/2026 1:10:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/28/2026 11:55:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 45m
FlixBus	26h 10m	5:15 PM	Gainesville, FL	Rosa Parks Transfer station	6:25 PM	Chicago	95th Red Line Station	Economy	$106	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/28/2026 5:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 6:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 26h 10m
FlixBus	30h 30m	6:05 PM	Gainesville, FL	Rosa Parks Transfer station	11:35 PM	Chicago	95th Red Line Station	Economy	$113	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/28/2026 6:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 11:35:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 30h 30m
Greyhound US	35h 5m	1:30 PM	Gainesville, FL	Greyhound Bus Station	11:35 PM	Chicago	95th Red Line Station	Economy	$113	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 7/28/2026 1:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 11:35:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 35h 5m
Greyhound US	29h 55m	8:20 AM	Gainesville, FL	Greyhound Bus Station	1:15 PM	Chicago	95th Red Line Station	Economy	$120	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 7/28/2026 8:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 7/29/2026 1:15:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 29h 55m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 0m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	12:10 AM	Chicago	Downtown Bus Station	Economy	$116	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/30/2026 1:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/31/2026 12:10:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 24h 0m
FlixBus	25h 0m	11:30 AM	Gainesville, FL	Rosa Parks Transfer station	11:30 AM	Chicago	Downtown Bus Station	Economy	$122	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/30/2026 11:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/31/2026 11:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 25h 0m
Greyhound US	28h 10m	8:20 AM	Gainesville, FL	Greyhound Bus Station	11:30 AM	Chicago	Downtown Bus Station	Economy	$122	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 7/30/2026 8:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/31/2026 11:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 28h 10m
FlixBus	27h 5m	6:05 PM	Gainesville, FL	Rosa Parks Transfer station	8:10 PM	Chicago	Downtown Bus Station	Economy	$125	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/30/2026 6:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 7/31/2026 8:10:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 27h 5m
Greyhound US	31h 40m	1:30 PM	Gainesville, FL	Greyhound Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$125	A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 7/30/2026 1:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 7/31/2026 8:10:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 31h 40m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	26h 10m	5:15 PM	Gainesville, FL	Rosa Parks Transfer station	6:25 PM	Chicago	95th Red Line Station	Economy	$103	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/31/2026 5:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 6:25:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 26h 10m
FlixBus	29h 10m	1:10 AM	Gainesville, FL	Rosa Parks Transfer station	5:20 AM	Chicago	95th Red Line Station	Economy	$105	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/31/2026 1:10:00 AM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 5:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 29h 10m
FlixBus	24h 35m	11:30 AM	Gainesville, FL	Rosa Parks Transfer station	11:05 AM	Chicago	95th Red Line Station	Economy	$105	A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 7/31/2026 11:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 11:05:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 24h 35m
Greyhound US	27h 45m	8:20 AM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$105	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/31/2026 8:20:00 AM to 95th Red Line Station, Chicago (USA) arriving at 8/1/2026 11:05:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 27h 45m
Greyhound US	28h 10m	8:20 AM	Gainesville, FL	North Walmart Supercenter Bus Stop	11:30 AM	Chicago	Downtown Bus Station	Economy	$113	A Bus from Greyhound US goes from North Walmart Supercenter Bus Stop, Gainesville, FL (USA) at 7/31/2026 8:20:00 AM to Downtown Bus Station, Chicago (USA) arriving at 8/1/2026 11:30:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 28h 10m

Frequency of bus connections between Gainesville, FL and Chicago

See here how frequent the connections between Gainesville, FL and Chicago are, during different times and days of the week.

Saturday is the busiest day, with more than 42 daily buses from Gainesville, FL to Chicago. Tuesday has instead the fewest connections, with only 7 daily coaches between Gainesville, FL and Chicago.

The busiest time of the day is the Morning, with 69 buses from Gainesville, FL to Chicago, while Night sees the fewest connections between Gainesville, FL and Chicago, with 15 offers.

Test cheapest views

The cheapest bus for the 7/20/2026 costs just $96, from FlixBus

Facts about the bus from Gainesville, FL to Chicago

Compare all providers like FlixBus and Greyhound US that travel 25 times every day by bus from Gainesville, FL to Chicago in one click! Book your bus ticket from Gainesville, FL to Chicago starting from $96!

Cheapest Bus	$96
Fastest Bus	22h 0m
Earliest Bus	1:10 AM
Latest Bus	9:20 PM
Daily Bus Routes	25 Ø
Distance	895.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Gainesville, FL to Chicago

Every day, 25 buses from 2 bus companies leave Gainesville, FL for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/25/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

Friday 07/24

Saturday 07/25

$99

Sunday 07/26

$106

Monday 07/27

$102

Tuesday 07/28

$105

Wednesday 07/29

Thursday 07/30

$105

Friday 07/31

$113

Saturday 08/01

$112

Sunday 08/02

$103

Monday 08/03

$120

Tuesday 08/04

Wednesday 08/05

$110

Thursday 08/06

$110

Friday 08/07

$110

Saturday 08/08

$121

Sunday 08/09

$112

Monday 08/10

$104

Tuesday 08/11

$112

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Gainesville, FL to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Gainesville, FL to Chicago, for the next 30 days.

With a price starting from $99, Saturday is the cheapest day for a bus from Gainesville, FL to Chicago. Thursday instead is the most expensive day with prices starting from $105.

Night is the cheapest day time for bus tickets from Gainesville, FL to Chicago, with $99. Evening is the most expensive time of the day with prices starting from $105.

How to save money travelling from Gainesville, FL to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Gainesville, FL to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Gainesville, FL to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Gainesville, FL to Chicago are also emptier.

All bus stations and stops in Gainesville, FL and Chicago

In the map below, you can see where to find all bus stations in Gainesville, FL and Chicago.

Rosa Parks Transfer station

SE 3rd St 700

Greyhound Bus Station

Northeast 23rd Avenue 101

Central Bus Station

North Walmart Supercenter Bus Stop

Westgate Plaza Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Gainesville, FL to Chicago

Want to know which seat classes are available on the buses from Gainesville, FL to Chicago? Or which bus companies serve the route Gainesville, FL to Chicago? Below you will find answers to your questions.

FAQs about the Gainesville, FL to Chicago bus

How much does a Gainesville, FL Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $96 and takes 22h 45m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Gainesville, FL to Chicago?

This route is offered by 2 companies with a range of ticket prices between $96 and $160. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Gainesville, FL to Chicago each day?

Every day, the Gainesville, FL to Chicago bus route is served by approximately 25 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Gainesville, FL to Chicago take?

The fastest bus from Gainesville, FL to Chicago is offered by FlixBus and takes 22h 0m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Gainesville, FL to Chicago?

The earliest bus arriving in Chicago from Gainesville, FL starts at 1:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Gainesville, FL to Chicago?

The latest bus trip departing from Gainesville, FL for Chicago starts at 9:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Gainesville, FL Chicago route?

When traveling by bus from Gainesville, FL to Chicago, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Gainesville, FL and Chicago?

You can check all the direct connections between Gainesville, FL and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Gainesville, FL to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Gainesville, FL Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Gainesville, FL Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Gainesville, FL to Chicago on your planned travel date.

Available seat classes which are offered on the bus route Gainesville, FL to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Gainesville, FL and to Chicago

Here’s an overview of the most popular bus routes to Gainesville, FL and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!