Bus Detroit to Louisville, KY - Compare all Companies

Compare all timetables for the bus from Detroit to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Detroit to Louisville, KY from various bus operators like Greyhound US for the next days.

today

$51

tomorrow

Wednesday

Thursday

$52

Friday

$54

Saturday

$54

Sunday

$60

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 25m	7:30 PM	Detroit	Central Bus Station	2:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$51	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/27/2026 7:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/28/2026 2:55:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 7h 25m
Greyhound US	14h 0m	11:15 PM	Detroit	Central Bus Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$64	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/27/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/28/2026 1:15:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 14h 0m
Greyhound US	7h 45m	1:50 PM	Detroit	Central Bus Station	9:35 PM	Louisville, KY	Greyhound Bus Station	Economy	$65	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/27/2026 1:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/27/2026 9:35:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 7h 45m
Greyhound US	11h 0m	7:55 PM	Detroit	Central Bus Station	6:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$65	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/27/2026 7:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/28/2026 6:55:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 11h 0m
Greyhound US	13h 10m	11:00 PM	Detroit	Central Bus Station	12:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$66	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/27/2026 11:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/28/2026 12:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 25m	7:30 PM	Detroit	Central Bus Station	2:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$52	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/30/2026 7:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/31/2026 2:55:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 7h 25m
Greyhound US	7h 45m	1:50 PM	Detroit	Central Bus Station	9:35 PM	Louisville, KY	Greyhound Bus Station	Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/30/2026 1:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/30/2026 9:35:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 7h 45m
Greyhound US	14h 0m	11:15 PM	Detroit	Central Bus Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$56	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/30/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/31/2026 1:15:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 14h 0m
Greyhound US	11h 0m	7:55 PM	Detroit	Central Bus Station	6:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$57	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/30/2026 7:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/31/2026 6:55:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 0m
Greyhound US	13h 10m	11:00 PM	Detroit	Central Bus Station	12:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$57	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/30/2026 11:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/31/2026 12:10:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 13h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 25m	7:30 PM	Detroit	Central Bus Station	2:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/31/2026 7:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/1/2026 2:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 7h 25m
Greyhound US	7h 45m	1:50 PM	Detroit	Central Bus Station	9:35 PM	Louisville, KY	Greyhound Bus Station	Economy	$58	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/31/2026 1:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 7/31/2026 9:35:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 7h 45m
Greyhound US	13h 10m	11:00 PM	Detroit	Central Bus Station	12:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$63	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/31/2026 11:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/1/2026 12:10:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 10m
Greyhound US	14h 0m	11:15 PM	Detroit	Central Bus Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$64	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/31/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/1/2026 1:15:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 14h 0m
Greyhound US	11h 0m	7:55 PM	Detroit	Central Bus Station	6:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/31/2026 7:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/1/2026 6:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 11h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 25m	7:30 PM	Detroit	Central Bus Station	2:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$54	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/1/2026 7:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/2/2026 2:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 7h 25m
Greyhound US	7h 45m	1:50 PM	Detroit	Central Bus Station	9:35 PM	Louisville, KY	Greyhound Bus Station	Economy	$58	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/1/2026 1:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/1/2026 9:35:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 7h 45m
Greyhound US	13h 10m	11:00 PM	Detroit	Central Bus Station	12:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$66	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/1/2026 11:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/2/2026 12:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 10m
Greyhound US	14h 0m	11:15 PM	Detroit	Central Bus Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$66	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/1/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/2/2026 1:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 14h 0m
Greyhound US	11h 0m	7:55 PM	Detroit	Central Bus Station	6:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$67	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/1/2026 7:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/2/2026 6:55:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 25m	7:30 PM	Detroit	Central Bus Station	2:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$60	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/2/2026 7:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/3/2026 2:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 7h 25m
Greyhound US	7h 45m	1:50 PM	Detroit	Central Bus Station	9:35 PM	Louisville, KY	Greyhound Bus Station	Economy	$65	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/2/2026 1:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/2/2026 9:35:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 7h 45m
Greyhound US	11h 0m	7:55 PM	Detroit	Central Bus Station	6:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/2/2026 7:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/3/2026 6:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 11h 0m
Greyhound US	14h 0m	11:15 PM	Detroit	Central Bus Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/2/2026 11:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/3/2026 1:15:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 14h 0m
Greyhound US	13h 10m	11:00 PM	Detroit	Central Bus Station	12:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$75	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 8/2/2026 11:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 8/3/2026 12:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 10m

Best Price Offer: The price for the cheapest bus from Detroit to Louisville, KY is $49 on 8/5/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Detroit and Louisville, KY

See here how frequent the connections between Detroit and Louisville, KY are, during different times and days of the week.

Thursday is the busiest day, with more than 10 daily buses from Detroit to Louisville, KY. Sunday has instead the fewest connections, with only 5 daily coaches between Detroit and Louisville, KY.

The busiest time of the day is the Evening, with 24 buses from Detroit to Louisville, KY, while Afternoon sees the fewest connections between Detroit and Louisville, KY, with 6 offers.

Facts about the bus from Detroit to Louisville, KY

Compare all providers like Greyhound US that travel 6 times every day by bus from Detroit to Louisville, KY in one click! Book your bus ticket from Detroit to Louisville, KY starting from $49!

Cheapest Bus	$49
Fastest Bus	7h 25m
Earliest Bus	1:50 PM
Latest Bus	11:15 PM
Daily Bus Routes	6 Ø
Distance	316.0 miles
Bus Companies	Greyhound US

Cheapest bus connections from Detroit to Louisville, KY

Every day, 6 buses from 1 bus companies leave Detroit for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$51

Tuesday 07/28

Wednesday 07/29

Thursday 07/30

$56

Friday 07/31

$54

Saturday 08/01

$54

Sunday 08/02

$60

Monday 08/03

$51

Tuesday 08/04

$54

Wednesday 08/05

$49

Thursday 08/06

$51

Friday 08/07

$51

Saturday 08/08

$54

Sunday 08/09

$60

Monday 08/10

Tuesday 08/11

Wednesday 08/12

$49

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

$56

Monday 08/17

$52

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Detroit to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Detroit to Louisville, KY, for the next 30 days.

With a price starting from $51, Monday is the cheapest day for a bus from Detroit to Louisville, KY. Sunday instead is the most expensive day with prices starting from $56.

Evening is the cheapest day time for bus tickets from Detroit to Louisville, KY, with $51. Afternoon is the most expensive time of the day with prices starting from $54.

How to save money travelling from Detroit to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Detroit to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Detroit to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Detroit to Louisville, KY are also emptier.

Beloved bus companies from Detroit to Louisville, KY

These are the most booked bus companies between Detroit to Louisville, KY from our users.

Greyhound US from Detroit to Louisville, KY

Here you will find the key facts about the Greyhound US bus route Detroit to Louisville, KY:

Cheapest Price	$51
Fastest Bus	7h 25m
Earliest Bus	1:50 PM
Last Bus	11:15 PM
Daily Connections	6 Ø
Found on	7/2/2026

All bus stations and stops in Detroit and Louisville, KY

In the map below, you can see where to find all bus stations in Detroit and Louisville, KY.

Central Bus Station

Howard St 1001

Amtrak

W Baltimore Ave 78

VA Medical Center Blue Deck

East Canfield Street (between John R. and Brush St.) 225

Park Avenue

Rosa Parks TC

Cass Ave 1310

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Service and Comfort on the bus from Detroit to Louisville, KY

Want to know which seat classes are available on the buses from Detroit to Louisville, KY? Or which bus companies serve the route Detroit to Louisville, KY? Below you will find answers to your questions.

FAQs about the Detroit to Louisville, KY bus

How much does a Detroit Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $49 and takes 7h 25m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Detroit to Louisville, KY?

This route is offered by 1 companies with a range of ticket prices between $49 and $75. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Detroit to Louisville, KY each day?

Every day, the Detroit to Louisville, KY bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Detroit to Louisville, KY take?

The fastest bus from Detroit to Louisville, KY is offered by Greyhound US and takes 7h 25m. Bus tickets for this connection cost $51. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Detroit to Louisville, KY?

The earliest bus arriving in Louisville, KY from Detroit starts at 1:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Detroit to Louisville, KY?

The latest bus trip departing from Detroit for Louisville, KY starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Detroit Louisville, KY route?

When traveling by bus from Detroit to Louisville, KY, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Detroit and Louisville, KY?

You can check all the direct connections between Detroit and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Detroit to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Detroit Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Detroit Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Detroit to Louisville, KY on your planned travel date.

Available seat classes which are offered on the bus route Detroit to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Detroit and to Louisville, KY

Here’s an overview of the most popular bus routes to Detroit and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!