Bus Chicago to Santiago de Queretaro

Compare all timetables for the bus from Chicago to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from Chicago to Santiago de Queretaro from various bus operators like Greyhound US or FlixBus for the next days.

today

$132

tomorrow

Wednesday

Thursday

Friday

Saturday

$160

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 10m	10:30 PM	Chicago	Downtown Bus Station	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$132	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 7/27/2026 10:30:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/29/2026 6:40:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 45h 10m
FlixBus	52h 0m	9:45 AM	Chicago	Downtown Bus Station	12:45 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$141	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 7/27/2026 9:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/29/2026 12:45:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 52h 0m
Greyhound US	68h 30m	11:10 PM	Chicago	Canal & Van Buren	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$150	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 7/27/2026 11:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/30/2026 6:40:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 68h 30m
Greyhound US	57h 25m	10:15 AM	Chicago	Canal & Van Buren	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$169	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 7/27/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/29/2026 6:40:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 57h 25m
FlixBus	48h 15m	7:25 PM	Chicago	95th Red Line Station	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$214	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 7/27/2026 7:25:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 7/29/2026 6:40:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 48h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	49h 20m	9:45 AM	Chicago	Downtown Bus Station	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$160	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 8/1/2026 9:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 10:05:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 49h 20m
Greyhound US	57h 25m	10:15 AM	Chicago	Canal & Van Buren	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$162	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/1/2026 10:15:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 6:40:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 57h 25m
Greyhound US	68h 30m	11:10 PM	Chicago	Canal & Van Buren	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$162	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 8/1/2026 11:10:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/4/2026 6:40:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 68h 30m
Greyhound US	45h 0m	10:40 PM	Chicago	Downtown Bus Station	6:40 PM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$183	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 8/1/2026 10:40:00 PM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 6:40:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 45h 0m
FlixBus	53h 20m	5:45 AM	Chicago	95th Red Line Station	10:05 AM	Santiago de Queretaro	Prol Zaragoza Y City Club Las Plazas Bus Stop	Economy	$217	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 8/1/2026 5:45:00 AM to Prol Zaragoza Y City Club Las Plazas Bus Stop, Santiago de Queretaro (Mexico) arriving at 8/3/2026 10:05:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 53h 20m

Best Price Offer: The price for the cheapest bus from Chicago to Santiago de Queretaro is $132 on 7/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Santiago de Queretaro

See here how frequent the connections between Chicago and Santiago de Queretaro are, during different times and days of the week.

Monday is the busiest day, with more than 10 daily buses from Chicago to Santiago de Queretaro. Saturday has instead the fewest connections, with only 7 daily coaches between Chicago and Santiago de Queretaro.

The busiest time of the day is the Evening, with 9 buses from Chicago to Santiago de Queretaro, while Night sees the fewest connections between Chicago and Santiago de Queretaro, with 2 offers.

Facts about the bus from Chicago to Santiago de Queretaro

Compare all providers like Greyhound US and FlixBus that travel 8 times every day by bus from Chicago to Santiago de Queretaro in one click! Book your bus ticket from Chicago to Santiago de Queretaro starting from $132!

Cheapest Bus	$132
Fastest Bus	44h 0m
Earliest Bus	5:45 AM
Latest Bus	11:55 PM
Daily Bus Routes	8 Ø
Distance	1,648.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Santiago de Queretaro

Every day, 8 buses from 2 bus companies leave Chicago for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$132

Tuesday 07/28

Wednesday 07/29

Thursday 07/30

Friday 07/31

Saturday 08/01

$160

Sunday 08/02

Monday 08/03

$179

Tuesday 08/04

$175

Wednesday 08/05

Thursday 08/06

Friday 08/07

$135

Saturday 08/08

$149

Sunday 08/09

Monday 08/10

$139

Tuesday 08/11

$149

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

$151

Sunday 08/16

Monday 08/17

Tuesday 08/18

$133

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

The cheapest time to travel from Chicago to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Santiago de Queretaro, for the next 30 days.

With a price starting from $132, Monday is the cheapest day for a bus from Chicago to Santiago de Queretaro. Saturday instead is the most expensive day with prices starting from $149.

Evening is the cheapest day time for bus tickets from Chicago to Santiago de Queretaro, with $132. Morning is the most expensive time of the day with prices starting from $141.

How to save money travelling from Chicago to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Santiago de Queretaro are also emptier.

All bus stations and stops in Chicago and Santiago de Queretaro

In the map below, you can see where to find all bus stations in Chicago and Santiago de Queretaro.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Service and Comfort on the bus from Chicago to Santiago de Queretaro

Want to know which seat classes are available on the buses from Chicago to Santiago de Queretaro? Or which bus companies serve the route Chicago to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the Chicago to Santiago de Queretaro bus

How much does a Chicago Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $132 and takes 44h 10m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from Chicago to Santiago de Queretaro?

This route is offered by 2 companies with a range of ticket prices between $132 and $238. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from Chicago to Santiago de Queretaro each day?

Every day, the Chicago to Santiago de Queretaro bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Santiago de Queretaro take?

The fastest bus from Chicago to Santiago de Queretaro is offered by Greyhound US and takes 44h 0m. Bus tickets for this connection cost $183. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from Chicago starts at 5:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Santiago de Queretaro?

The latest bus trip departing from Chicago for Santiago de Queretaro starts at 11:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Santiago de Queretaro route?

When traveling by bus from Chicago to Santiago de Queretaro, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Santiago de Queretaro?

You can check all the direct connections between Chicago and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Santiago de Queretaro on your planned travel date.

Available seat classes which are offered on the bus route Chicago to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to Chicago and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!