Bus Buenos Aires to Santa Cruz de la Sierra

Compare all timetables for the bus from Buenos Aires to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from Buenos Aires to Santa Cruz de la Sierra from various bus operators like La Preferida Bus for the next days.

today

$234

tomorrow

$234

Wednesday

Thursday

Friday

$168

Saturday

$168

Sunday

$245

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 0m	4:30 PM	Buenos Aires	Avenida Corrientes	6:30 AM	Santa Cruz de la Sierra	Terminal Bimodal		First Class	$234	A Bus from La Preferida Bus goes from Avenida Corrientes, Buenos Aires (Argentina) at 7/27/2026 4:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 7/29/2026 6:30:00 AM. 50 First Class ticket for $234 per person are available. Travel duration is 38h 0m

Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $68? You can find the corresponding connections below.
- Crucero del Norte
  
  51h 45m
  
  0
  
  1:15 PM
  
  Buenos Aires
  Retiro Bus Station
  
  8:45 AM
  
  Asunción, PY
  Bus Station Assunção
  
  0
  
  Premium Economy
  
  $75
  
  A Bus from Crucero del Norte goes from Retiro Bus Station, Buenos Aires (Argentina) at 7/28/2026 1:15:00 PM to Bus Station Assunção, Asunción, PY (Paraguay) arriving at 7/29/2026 8:45:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 19h 30m
- Stel Turismo SRL
  
  21h 0m
  
  0
  
  8:00 PM
  
  Asunción, PY
  Bus Station Assunção
  
  4:00 PM
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  Premium Economy
  
  $91
  
  A Bus from Stel Turismo SRL goes from Bus Station Assunção, Asunción, PY (Paraguay) at 7/29/2026 8:00:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 7/30/2026 4:00:00 PM. 50 Premium Economy ticket for $91 per person are available. Travel duration is 21h 0m
Travel time is 13h 45m longer, but you will save $68

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 0m	4:30 PM	Buenos Aires	Avenida Corrientes	6:30 AM	Santa Cruz de la Sierra	Terminal Bimodal		First Class	$234	A Bus from La Preferida Bus goes from Avenida Corrientes, Buenos Aires (Argentina) at 7/28/2026 4:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 7/30/2026 6:30:00 AM. 50 First Class ticket for $234 per person are available. Travel duration is 38h 0m

Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $68? You can find the corresponding connections below.
- Crucero del Norte
  
  51h 45m
  
  0
  
  1:15 PM
  
  Buenos Aires
  Retiro Bus Station
  
  8:45 AM
  
  Asunción, PY
  Bus Station Assunção
  
  0
  
  Premium Economy
  
  $75
  
  A Bus from Crucero del Norte goes from Retiro Bus Station, Buenos Aires (Argentina) at 7/28/2026 1:15:00 PM to Bus Station Assunção, Asunción, PY (Paraguay) arriving at 7/29/2026 8:45:00 AM. 50 Premium Economy ticket for $75 per person are available. Travel duration is 19h 30m
- Stel Turismo SRL
  
  21h 0m
  
  0
  
  8:00 PM
  
  Asunción, PY
  Bus Station Assunção
  
  4:00 PM
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  Premium Economy
  
  $91
  
  A Bus from Stel Turismo SRL goes from Bus Station Assunção, Asunción, PY (Paraguay) at 7/29/2026 8:00:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 7/30/2026 4:00:00 PM. 50 Premium Economy ticket for $91 per person are available. Travel duration is 21h 0m
Travel time is 13h 45m longer, but you will save $68

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 0m	4:30 PM	Buenos Aires	Avenida Corrientes	6:30 AM	Santa Cruz de la Sierra	Terminal Bimodal		First Class	$168	A Bus from La Preferida Bus goes from Avenida Corrientes, Buenos Aires (Argentina) at 7/31/2026 4:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/2/2026 6:30:00 AM. 50 First Class ticket for $168 per person are available. Travel duration is 38h 0m

Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Tarija, you can save more than $41? You can find the corresponding connections below.
- Expreso Transamericano
  
  43h 30m
  
  0
  
  11:00 AM
  
  Buenos Aires
  Retiro Bus Station
  
  4:35 PM
  
  Tarija
  Nueva Terminal de Buses
  
  0
  
  Premium Economy
  
  $108
  
  A Bus from Expreso Transamericano goes from Retiro Bus Station, Buenos Aires (Argentina) at 8/1/2026 11:00:00 AM to Nueva Terminal de Buses, Tarija (Bolivia) arriving at 8/2/2026 4:35:00 PM. 50 Premium Economy ticket for $108 per person are available. Travel duration is 30h 35m
- Lince SRL
  
  12h 0m
  
  0
  
  5:30 PM
  
  Tarija
  Nueva Terminal de Buses
  
  5:30 AM
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  First Class
  
  $19
  
  A Bus from Lince SRL goes from Nueva Terminal de Buses, Tarija (Bolivia) at 8/2/2026 5:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/3/2026 5:30:00 AM. 50 First Class ticket for $19 per person are available. Travel duration is 12h 0m
Travel time is 5h 30m longer, but you will save $41

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	38h 0m	4:30 PM	Buenos Aires	Avenida Corrientes	6:30 AM	Santa Cruz de la Sierra	Terminal Bimodal		First Class	$168	A Bus from La Preferida Bus goes from Avenida Corrientes, Buenos Aires (Argentina) at 8/1/2026 4:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/3/2026 6:30:00 AM. 50 First Class ticket for $168 per person are available. Travel duration is 38h 0m

Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Tarija, you can save more than $41? You can find the corresponding connections below.
- Expreso Transamericano
  
  43h 30m
  
  0
  
  11:00 AM
  
  Buenos Aires
  Retiro Bus Station
  
  4:35 PM
  
  Tarija
  Nueva Terminal de Buses
  
  0
  
  Premium Economy
  
  $108
  
  A Bus from Expreso Transamericano goes from Retiro Bus Station, Buenos Aires (Argentina) at 8/1/2026 11:00:00 AM to Nueva Terminal de Buses, Tarija (Bolivia) arriving at 8/2/2026 4:35:00 PM. 50 Premium Economy ticket for $108 per person are available. Travel duration is 30h 35m
- Lince SRL
  
  12h 0m
  
  0
  
  5:30 PM
  
  Tarija
  Nueva Terminal de Buses
  
  5:30 AM
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  First Class
  
  $19
  
  A Bus from Lince SRL goes from Nueva Terminal de Buses, Tarija (Bolivia) at 8/2/2026 5:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/3/2026 5:30:00 AM. 50 First Class ticket for $19 per person are available. Travel duration is 12h 0m
Travel time is 5h 30m longer, but you will save $41

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	La Preferida Bus	39h 0m	4:30 PM	Buenos Aires	Liniers Bus Station	6:30 AM	Santa Cruz de la Sierra	Terminal Bimodal		First Class	$245	A Bus from La Preferida Bus goes from Liniers Bus Station, Buenos Aires (Argentina) at 8/2/2026 4:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/4/2026 6:30:00 AM. 50 First Class ticket for $245 per person are available. Travel duration is 39h 0m

Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Tarija, you can save more than $118? You can find the corresponding connections below.
- Expreso Transamericano
  
  43h 30m
  
  0
  
  11:00 AM
  
  Buenos Aires
  Retiro Bus Station
  
  4:35 PM
  
  Tarija
  Nueva Terminal de Buses
  
  0
  
  Premium Economy
  
  $108
  
  A Bus from Expreso Transamericano goes from Retiro Bus Station, Buenos Aires (Argentina) at 8/1/2026 11:00:00 AM to Nueva Terminal de Buses, Tarija (Bolivia) arriving at 8/2/2026 4:35:00 PM. 50 Premium Economy ticket for $108 per person are available. Travel duration is 30h 35m
- Lince SRL
  
  12h 0m
  
  0
  
  5:30 PM
  
  Tarija
  Nueva Terminal de Buses
  
  5:30 AM
  
  Santa Cruz de la Sierra
  Terminal Bimodal
  
  0
  
  First Class
  
  $19
  
  A Bus from Lince SRL goes from Nueva Terminal de Buses, Tarija (Bolivia) at 8/2/2026 5:30:00 PM to Terminal Bimodal, Santa Cruz de la Sierra (Bolivia) arriving at 8/3/2026 5:30:00 AM. 50 First Class ticket for $19 per person are available. Travel duration is 12h 0m
Travel time is 5h 30m longer, but you will save $118

Best Price Offer: The price for the cheapest bus from Buenos Aires to Santa Cruz de la Sierra is $135 on 7/27/2026. Flexible travelers save on ticket prices.

Facts about the bus from Buenos Aires to Santa Cruz de la Sierra

Compare all providers like La Preferida Bus that travel 1 times every day by bus from Buenos Aires to Santa Cruz de la Sierra in one click! Book your bus ticket from Buenos Aires to Santa Cruz de la Sierra starting from $135!

Cheapest Bus	$135
Fastest Bus	38h 0m
Earliest Bus	4:30 PM
Latest Bus	4:30 PM
Daily Bus Routes	1 Ø
Distance	1,199.3 miles
Bus Companies	La Preferida Bus

Cheapest bus connections from Buenos Aires to Santa Cruz de la Sierra

Every day, 1 buses from 1 bus companies leave Buenos Aires for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/26

Monday 07/27

$135

Tuesday 07/28

$234

Wednesday 07/29

$234

Thursday 07/30

Friday 07/31

$168

Saturday 08/01

$168

Sunday 08/02

$245

Monday 08/03

$245

Tuesday 08/04

$135

Wednesday 08/05

Thursday 08/06

$177

Friday 08/07

$168

Saturday 08/08

Sunday 08/09

$168

Monday 08/10

Tuesday 08/11

$245

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

Sunday 08/16

Monday 08/17

Tuesday 08/18

Wednesday 08/19

Thursday 08/20

Friday 08/21

Saturday 08/22

How to save money travelling from Buenos Aires to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buenos Aires to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buenos Aires to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buenos Aires to Santa Cruz de la Sierra are also emptier.

All bus stations and stops in Buenos Aires and Santa Cruz de la Sierra

In the map below, you can see where to find all bus stations in Buenos Aires and Santa Cruz de la Sierra.

Liniers Bus Station

Avenida General Paz , Liniers 10868/76

Retiro Bus Station

Av. Antártida Argentina y Calle 10 - Capital Federal. 10

Terminal de Ómnibus Dellepiane

Teniente General Luís Dellepiane Av. Perito Moreno 3950, Villa Soldati, Ciudad de Buenos Aires

Villa Tesei

Reyes Catolicos 246

Thames - Panamericana

Terminal Bimodal

Av Intermodal

Service and Comfort on the bus from Buenos Aires to Santa Cruz de la Sierra

Want to know which seat classes are available on the buses from Buenos Aires to Santa Cruz de la Sierra? Or which bus companies serve the route Buenos Aires to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the Buenos Aires to Santa Cruz de la Sierra bus

How much does a Buenos Aires Santa Cruz de la Sierra bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $135 and takes 38h 0m to reach Santa Cruz de la Sierra. Compare offers to save money!

How much could I save by comparing buses from Buenos Aires to Santa Cruz de la Sierra?

This route is offered by 1 companies with a range of ticket prices between $135 and $245. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Cruz de la Sierra.

On average, how many connections are available from Buenos Aires to Santa Cruz de la Sierra each day?

Every day, the Buenos Aires to Santa Cruz de la Sierra bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buenos Aires to Santa Cruz de la Sierra take?

The fastest bus from Buenos Aires to Santa Cruz de la Sierra is offered by La Preferida Bus and takes 38h 0m. Bus tickets for this connection cost $234. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buenos Aires to Santa Cruz de la Sierra?

The earliest bus arriving in Santa Cruz de la Sierra from Buenos Aires starts at 4:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buenos Aires to Santa Cruz de la Sierra?

The latest bus trip departing from Buenos Aires for Santa Cruz de la Sierra starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buenos Aires Santa Cruz de la Sierra route?

When traveling by bus from Buenos Aires to Santa Cruz de la Sierra, passengers can travel with La Preferida Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buenos Aires and Santa Cruz de la Sierra?

You can check all the direct connections between Buenos Aires and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: La Preferida Bus.

What can I take with me on the Buenos Aires to Santa Cruz de la Sierra bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buenos Aires Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buenos Aires Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buenos Aires to Santa Cruz de la Sierra on your planned travel date.

Available seat classes which are offered on the bus route Buenos Aires to Santa Cruz de la Sierra

First Class

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Buenos Aires and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to Buenos Aires and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!