Which bus from Antofagasta to La Serena is the cheapest?

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Compare all timetables for the bus from Antofagasta to La Serena

Here is a selection of the cheapest bus trips from the schedule from Antofagasta to La Serena from various bus operators like Pullman San Andres, Pluss Chile or Cikbus Elité for the next days.

today
$25
tomorrow
$21
Tuesday
$23
Wednesday
$23
Thursday
$22
Friday
$22
Saturday
$22

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 12h 10m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM La Serena Central Bus Station  Economy $25
FlixBus 12h 10m 11:20 PM Antofagasta Carlos Oviedo Cavada Bus Station 11:30 AM La Serena Central Bus Station  Business $29
Cormar Bus 11h 50m 2:00 PM Antofagasta Camus Bus Station 1:50 AM La Serena Central Bus Station  Premium Economy $32
Pullman San Andres 12h 10m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 1:10 AM La Serena Central Bus Station  Premium Economy $34
Pullman Bus 11h 35m 10:30 AM Antofagasta Camus Bus Station 10:05 PM La Serena El Sto, 1060  First Class $45

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $21
FlixBus 12h 10m 1:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 1:45 PM La Serena Central Bus Station  Economy $23
Pullman Bus 11h 50m 1:00 AM Antofagasta Camus Bus Station 12:50 PM La Serena El Sto, 1060  First Class $30
Pullman Bus 11h 35m 10:30 AM Antofagasta Camus Bus Station 10:05 PM La Serena El Sto, 1060  First Class $30
Pullman San Andres 12h 10m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:40 PM La Serena Central Bus Station  Premium Economy $34

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 12h 10m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM La Serena Central Bus Station  Economy $23
FlixBus 12h 10m 6:20 PM Antofagasta Carlos Oviedo Cavada Bus Station 6:30 AM La Serena Central Bus Station  Economy $23
Pullman Bus 11h 50m 1:00 AM Antofagasta Camus Bus Station 12:50 PM La Serena El Sto, 1060  First Class $30
Pullman San Andres 12h 10m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:40 PM La Serena Central Bus Station  Premium Economy $34
Cormar Bus 11h 50m 2:00 PM Antofagasta Camus Bus Station 1:50 AM La Serena Central Bus Station  Premium Economy $35

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 12h 10m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM La Serena Central Bus Station  Economy $23
FlixBus 12h 10m 11:20 PM Antofagasta Carlos Oviedo Cavada Bus Station 11:30 AM La Serena Central Bus Station  Business $28
Cormar Bus 11h 50m 1:00 AM Antofagasta Camus Bus Station 12:50 PM La Serena Central Bus Station  Premium Economy $32
Pullman San Andres 12h 10m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 1:10 AM La Serena Central Bus Station  Premium Economy $32
Cikbus Elité 11h 20m 1:10 AM Antofagasta Carlos Oviedo Cavada Bus Station 12:30 PM La Serena Central Bus Station  Premium Economy $36

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 12h 10m 6:20 PM Antofagasta Carlos Oviedo Cavada Bus Station 6:30 AM La Serena Central Bus Station  Economy $22
Pullman San Andres 12h 10m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:40 PM La Serena Central Bus Station  Premium Economy $34
Cormar Bus 11h 50m 2:00 PM Antofagasta Camus Bus Station 1:50 AM La Serena Central Bus Station  Premium Economy $35
Cikbus Elité 11h 20m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 2:50 PM La Serena Central Bus Station  Premium Economy $36
Pluss Chile 10h 45m 12:05 AM Antofagasta Carlos Oviedo Cavada Bus Station 10:50 AM La Serena Central Bus Station  Premium Economy $37

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 12h 10m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM La Serena Central Bus Station  Economy $22
FlixBus 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $24
Pullman San Andres 12h 10m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:40 PM La Serena Central Bus Station  Premium Economy $34
Pullman San Andres 12h 10m 1:00 PM Antofagasta Carlos Oviedo Cavada Bus Station 1:10 AM La Serena Central Bus Station  Premium Economy $34
Cormar Bus 11h 50m 2:00 PM Antofagasta Camus Bus Station 1:50 AM La Serena Central Bus Station  Premium Economy $35

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 12h 10m 9:50 PM Antofagasta Carlos Oviedo Cavada Bus Station 10:00 AM La Serena Central Bus Station  Economy $22
FlixBus 12h 10m 3:35 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:45 PM La Serena Central Bus Station  Economy $22
Pullman San Andres 12h 10m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 3:40 PM La Serena Central Bus Station  Premium Economy $34
Cormar Bus 11h 50m 2:00 PM Antofagasta Camus Bus Station 1:50 AM La Serena Central Bus Station  Premium Economy $35
Cikbus Elité 11h 20m 3:30 AM Antofagasta Carlos Oviedo Cavada Bus Station 2:50 PM La Serena Central Bus Station  Premium Economy $36

Best Price Offer: The price for the cheapest bus from Antofagasta to La Serena is $21 on 7/27/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Antofagasta and La Serena

See here how frequent the connections between Antofagasta and La Serena are, during different times and days of the week.
Wednesday is the busiest day, with more than 119 daily buses from Antofagasta to La Serena. Sunday has instead the fewest connections, with only 37 daily coaches between Antofagasta and La Serena.
The busiest time of the day is the Evening, with 237 buses from Antofagasta to La Serena, while Morning sees the fewest connections between Antofagasta and La Serena, with 54 offers.

Facts about the bus from Antofagasta to La Serena

Compare all providers like Pullman San Andres, Pluss Chile and Cikbus Elité that travel 77 times every day by bus from Antofagasta to La Serena in one click! Book your bus ticket from Antofagasta to La Serena starting from $21!

Cheapest Bus $21
Fastest Bus 10h 30m
Earliest Bus 10:30 AM
Latest Bus 11:59 PM
Daily Bus Routes 77 Ø
Distance 435.4 miles
Bus Companies Pullman San Andres, Pluss Chile, Cikbus Elité, Pullman Bus, Cormar Bus, FlixBus and Nueva Andimar Vip

Cheapest bus connections from Antofagasta to La Serena

Every day, 77 buses from 7 bus companies leave Antofagasta for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/26/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/26
$29
Monday 07/27
$27
Tuesday 07/28
$26
Wednesday 07/29
$26
Thursday 07/30
$27
Friday 07/31
$27
Saturday 08/01
$22
Sunday 08/02
$28
Monday 08/03
$26
Tuesday 08/04
$23
Wednesday 08/05
$23
Thursday 08/06
$23
Friday 08/07
$22
Saturday 08/08
$32
Sunday 08/09
$28
Monday 08/10
$25
Tuesday 08/11
$34
Wednesday 08/12
$39
Thursday 08/13
$28
Friday 08/14
$32
Saturday 08/15
$29
Sunday 08/16
$36
Monday 08/17
$26
Tuesday 08/18
$28
Wednesday 08/19
$32
Thursday 08/20
$25
Friday 08/21
$31
Saturday 08/22

The cheapest time to travel from Antofagasta to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to La Serena, for the next 30 days.
With a price starting from $21, Monday is the cheapest day for a bus from Antofagasta to La Serena. Sunday instead is the most expensive day with prices starting from $25.
Night is the cheapest day time for bus tickets from Antofagasta to La Serena, with $21. Morning is the most expensive time of the day with prices starting from $30.

How to save money travelling from Antofagasta to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Antofagasta to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Antofagasta to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Antofagasta to La Serena are also emptier.

Latest reviews for bus companies on the route Antofagasta - La Serena

Pullman San Andres
Cecilia Yanet Castro Ordenes, 1/18/2026
Pésima experiencias en Pullman San Andrés. Horarios: atrasos de hasta dos horas. Bus sucio y en mal estado. Al bus le faltaba la puerta del segundo piso y la puerta del baño no se cerraba, golpeándose ... Pésima experiencias en Pullman San Andrés. Horarios: atrasos de hasta dos horas. Bus sucio y en mal estado. Al bus le faltaba la puerta del segundo piso y la puerta del baño no se cerraba, golpeándose durante todo el viaje y dejando salir los malos olores. En la escalera había apoyada una escoba que también golpeaba durante todo el viaje. El chofer muy imprudente en su manejo, poco confortable, exceso de velocidad y frenadas constantes. Además, condujo por más de cinco horas que es lo establecido. Poquísimo personal, no hay a quien solicitar ayuda si la necesitas. No lo recomiendo y me preocupa la falta de fiscalización que permite este tipo de servicio en viajes largos.
Cikbus Elité
Alfonso fuentes , 3/22/2025
Muy mala puntualidad ya que teniamos que salir a las 23:30 horas desde antofagasta y terminamos saliendo a las 12 de la madrugada, ademas de eso el bus venia por gran parte del trayecto a mas de 120 k ... Muy mala puntualidad ya que teniamos que salir a las 23:30 horas desde antofagasta y terminamos saliendo a las 12 de la madrugada, ademas de eso el bus venia por gran parte del trayecto a mas de 120 kmh, ademas de eso se quedan haciendo tiempo en chañaral para poder llegar en el horario indicado ademas de eso me cambiaron el pasaje en 2 oportunidades por problemas con sus maquinas por nada del mundo compren pasajes en cikbus

All bus stations and stops in Antofagasta and La Serena

In the map below, you can see where to find all bus stations in Antofagasta and La Serena.

Service and Comfort on the bus from Antofagasta to La Serena

Want to know which seat classes are available on the buses from Antofagasta to La Serena? Or which bus companies serve the route Antofagasta to La Serena? Below you will find answers to your questions.

FAQs about the Antofagasta to La Serena bus

How much does a Antofagasta La Serena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 12h 10m to reach La Serena. Compare offers to save money!

How much could I save by comparing buses from Antofagasta to La Serena?

This route is offered by 7 companies with a range of ticket prices between $21 and $59. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to La Serena.

On average, how many connections are available from Antofagasta to La Serena each day?

Every day, the Antofagasta to La Serena bus route is served by approximately 77 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Antofagasta to La Serena take?

The fastest bus from Antofagasta to La Serena is offered by Cormar Bus and takes 10h 30m. Bus tickets for this connection cost $37. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Antofagasta to La Serena?

The earliest bus arriving in La Serena from Antofagasta starts at 10:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Antofagasta to La Serena?

The latest bus trip departing from Antofagasta for La Serena starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Antofagasta La Serena route?

When traveling by bus from Antofagasta to La Serena, passengers can travel with Pullman San Andres, Pluss Chile and Cikbus Elité. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Antofagasta and La Serena?

You can check all the direct connections between Antofagasta and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pluss Chile and Cikbus Elité.

What can I take with me on the Antofagasta to La Serena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Antofagasta La Serena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to La Serena on your planned travel date.

Available seat classes which are offered on the bus route Antofagasta to La Serena

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to La Serena

Here’s an overview of the most popular bus routes to Antofagasta and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!

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